(PDF) Antibodies for Infectious Diseases by James E. Crowe

This is the PDF eBook version for Antibodies for Infectious Diseases by James E. Crowe, Diana Boraschi, Rino Rappuoli

Table of Contents

Contributors

Preface

Introduction

1 History and Practice: Antibodies in Infectious Diseases

General Features of Immunoglobulins

2 Functions of Antibodies

3 Antibody Structure

4 The Role of Complement in Antibody Therapy for Infectious Diseases

5 Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment

Antibody Discovery Approaches

6 Phage and Yeast Display

7 Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells

8 Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies

9 Humanized Mice for Studying Human Immune Responses and Generating Human Monoclonal Antibodies

10 Antibodies: Computer-Aided Prediction of Structure and Design of Function

Pathogen-Specific Antibodies

11 Antibodies Targeting the Envelope of HIV-1

12 Committing the Oldest Sins in the Newest Kind of Ways—Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head

13 Prevention of Respiratory Syncytial Virus Infection: From Vaccine to Antibody

14 Human Metapneumovirus

15 Dengue Antibody-Dependent Enhancement: Knowns and Unknowns

16 Immunotherapeutic Approaches To Prevent Cytomegalovirus-Mediated Disease

17 Rotavirus

18 Bacterial Toxins—Staphylococcal Enterotoxin B

Technical Advances

19 Antibody Engineering

20 High-Throughput DNA Sequencing Analysis of Antibody Repertoires

21 Antibody Informatics: IMGT, the International ImMunoGeneTics Information System Strains

22 Probing Antibody-Antigen Interactions

23 Radiolabeled Antibodies for Therapy of Infectious Diseases

Alternate Systems for Expression

24 Plant-Derived Monoclonal Antibodies for Prevention and Treatment of Infectious Disease

25 Vector-Mediated In Vivo Antibody Expression

Index