(PDF) The Challenge of Highly Pathogenic Microorganisms by Avigdor Shafferman

This is the PDF eBook version for The Challenge of Highly Pathogenic Microorganisms – Mechanisms of Virulence and Novel Medical Countermeasures by Avigdor Shafferman, Baruch Velan, Arie Ordentlich

Table of Contents

The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics.- Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases.- Dynamics of Bacillus anthracis Infection and Control Mechanisms.- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages.- The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence.- The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence.- Dissection of the Functions of the IglC Protein of Francisella tularensis.- Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions.- The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization.- Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process.- Poxvirus Entry into Host Cells.- Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host.- Inhibitors of Innate Immunity from Vaccinia Virus.- Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts.- MMP-9 as a Marker for Vaccinia Virus Related Encephalitis.- Epidemic Cowpox Virus Infections in Germany.- The Two Partner SecretionTwo Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection.- Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX).- Subtyping Biothreat Bacterial Pathogens.- A Rapid Method for Bacillus anthracis Genotyping.- Tularemia – A Disease with an Uncertain Impact on Public Health.- Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections.- Novel Live Vaccine Candidates Against Airborne Francisella tularensis.- Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS).- Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates.- Modified Vaccinia Virus Ankara (MVA) based Vaccines – Immunostimulatory and Protective Capacity.- Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection.- A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity.- Protection Against Plague Afforded by Treatment with Polyclonal ?LcrV and ?F1 Antibodies.- Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect.- The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores.- Reverse Vaccinology in Bacillus anthracis Bacillus anthracis .