This is the PDF eBook version for Sample Sizes for Clinical, Laboratory and Epidemiology Studies 4th Edition by by David Machin, Michael J. Campbell, Say Beng Tan, Sze Huey Tan
Table of Contents
1 Basic Design Considerations 1
2 Further Design Considerations 29
3 Binary Outcomes 41
4 Ordered Categorical Outcomes 55
5 Continuous Outcomes 67
6 Rate Outcomes 83
7 Survival Time Outcomes 99
8 Paired Binary, Ordered Categorical and Continuous Outcomes 117
9 Confidence Intervals 137
10 Repeated Outcome Measures 157
11 Non-Inferiority and Equivalence 169
12 Cluster Designs 195
13 Stepped Wedge Designs 215
14 More than Two Groups Designs 229
15 Genomic Targets and Dose-Finding 239
16 Feasibility and Pilot Studies 251
17 Therapeutic Exploratory Trials: Single Arm with Binary Outcomes 269
18 Therapeutic Exploratory Trials: Survival, Dual Endpoints, Randomised and Genomic Targets 283
19 The Correlation Coefficient 305
20 Observer Agreement Studies 317
21 Reference Intervals and Receiver Operating Curves 339
22 Sample Size Software SSS 361
Cumulative References 363
Index 381