(PDF) Protein Deimination in Human Health and Disease by Anthony P Nichola

This is the PDF eBook version for Protein Deimination in Human Health and Disease by Anthony P Nicholas, Sanjoy K Bhattacharya

Table of Contents

Frontmatter
1. Physiological Pathways of PAD Activation and Citrullinated Epitope Generation
2. From Citrullination to Specific Immunity and Disease in Rheumatoid Arthritis
3. The Role of Synovial Citrullinated Proteins in the Pathophysiology of Rheumatoid Arthritis
4. Protein Citrullination: The Link Between Rheumatoid Arthritis and Periodontitis?
5. From Genes and Environment to Anti-citrulline Immunity in Rheumatoid Arthritis: The Role of the Lungs
6. Neutrophils and Their Contribution to Autoimmunity in Rheumatoid Arthritis
7. Deimination in Skin and Regulation of Peptidylarginine Deiminase Expression in Keratinocytes
8. Importance of Citrullination on Hair Protein Molecular Assembly During Trichocytic Differentiation
9. Deimination in the Peripheral Nervous System: A Wallflower Existence
10. Deimination in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
11. Protein Hypercitrullination in CNS Demyelinating Disease Reversed by PAD Inhibition
12. Deimination in Prion Diseases
13. Deimination in Alzheimer’s Disease
14. Ongoing Studies of Deimination in Neurodegenerative Diseases Using the F95 Antibody
15. The Role of Deimination as a Response to Trauma and Hypoxic Injury in the Developing CNS
16. Deimination in Ocular Tissues: Present and Future
17. PAD Enzymes in Female Reproductive Tissues and Cancer Pathogenesis
18. The Role of Protein Deimination in Epigenetics
19. Identifying Citrullination Sites by Mass Spectrometry
20. Homocitrulline: An Analog and Confounder Related to Citrulline
21. Picking the PAD Lock: Chemical and Biological Approaches to Identify PAD Substrates and Inhibitors
Backmatter