(PDF) Peptide-based Drug Discovery by Ved Srivastava

This is the PDF eBook version for Peptide-based Drug Discovery – Challenges and New Therapeutics by Ved Srivastava, Tomi Sawyer, David Rotella, Andrew Young, David Sabatino

Table of Contents

Renaissance in Peptide Drug Discovery: The Third Wave; Identification and Validation of Peptide Therapeutic Targets and Indications; Peptide Biomarkers and Assay Development; Peptide Libraries Technologies: Mixture Based Libraries Generation and Screening; Macrocyclic peptides for intracellular drug targets; Structural Design for Bioactive Peptides; Peptide Lead Optimization – Strategies and Tactics; ADME Properties of Peptide Therapeutics in Drug Discovery and Development; Optimizing Peptides for Metabolic Diseases; Peptide Therapeutics-Oncology; Development of Peptide-based Diagnostic and Therapeutic Agents in Oncology; Designing an Effective Peptide Vaccine; Peptide Therapeutics: Neuropeptides; From Spider Toxins to Therapeutics—Developing Selective Nav1.7 Peptide Inhibitors for Pain; Structure and Function of Stress Responsive Peptides in Insects; Technologies for Oral Delivery of Peptides; Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens; Solid-Phase Peptide Synthesis, the State of the Art: Challenges and Opportunities