(PDF) HCV – The Journey from Discovery to a Cure – Volume I by Michael J. Sofia

This is the PDF eBook version for HCV – The Journey from Discovery to a Cure – Volume I by Michael J. Sofia

Table of Contents

Identification of the virus, the medical need and clearing the blood supply.- Mapping the HCV genome.- The molecular virology of HCV.- The development of the HCV replicon system.- The Evolution of IFN therapy for HCV.- Evolution of HCV NS5B Non-Nucleoside Inhibitors.- Evolution of HCV NS5B Nucleoside & Nucleotide Inhibitors.- Discovery and Development of Sofosbuvir.- Discovery of Beclabuvir.- Discovery of Dasabuvir.- Evolution of HCV NS3/4 protease inhibitors.- Discovery and Development of Telaprevir.- Discovery and Development of Boceprevir.- Discovery and Development of Asunaprevir.-Discovery and Development of Grazoprevir.- Discovery and Development of Simeprevir.- Discovery and Development of Paritaprevir & Glecaprevir.