(PDF) Fragment-Based Drug Discovery by Steven Howard

This is the PDF eBook version for Fragment-Based Drug Discovery by Steven Howard, Chris Abell, Martin Drysdale, Daniel A Erlanson, Tony Giannetti

Table of Contents

Different flavours of Fragments; Advances in SPR Technology; Applications of NMR in Fragment-Based Drug Discovery; Issues around Fragments as an Approach, including a Computational/in silico Perspectives on Fragment-Based Drug Discovery; Fragment-Based Drug Discovery of Kinase Inhibitors; Fragment-Based Discovery of Antibacterials; Strategies for Fragment-Based Lead Generation; Fragment-Based Approaches to Epigenetic Targets; Application of Fragment-Based Drug Discovery to GPCRs; Fragment-Based Drug Discovery applied to Protein-Protein Interactions; Probing Difficult Targets