(PDF) Antisense Technology, Part B, Applications By John N. Abelson

This is the PDF eBook version for Antisense Technology, Part B, Applications By John N. Abelson, Melvin I. Simon

Table of Contents

Preface
Volumes in Series
Section I: Antisense Receptor Targets
Chapter 1. In Vivo Modulation of G Proteins and Opioid Receptor Function by Antisense Oligodeoxynucl
Chapter 2. Targeting Brain GABAA Receptors with Antisense Oligonucleotides: Implications for Epileps
Chapter 3. Delivery of Antisense DNA by Vectors for Prolonged Effects in Vitro and in Vivo
Chapter 4. Antisense Mapping: Assessing Functional Significance of Genes and Splice Variants
Chapter 5. In Vitro and in Vivo Effects of Antisense on alpha2-Adrenoceptor Expression
Chapter 6. Design and Efficacy of a Serotonin-2A Receptor Antisense Oligodeoxynucleotide
Chapter 7. Reduction of Neurotransmitter Receptor and G-Protein Expression in Vivo and in Vitro by A
Chapter 8. Use of Expression of Antisense mRNA for Convertases 1 and 2 in Prohormone Processing
Section II: Antisense Neuroscience Targets
Chapter 9. Strategies for the Design and Delivery of Antisense Oligonucleotides in Central Nervous S
Chapter 10. Use of Antisense Expression Plasmids to Attenuate G-Protein Expression in Primary Neuron
Chapter 11. Gene Functional Analysis in Nervous System
Chapter 12. RNA Mapping: Selection of Potent Oligonucleotide Sequences for Antisense Experiments
Chapter 13. Effects of Centrally Administered Antisense Oligodeoxynucleotides on Feeding Behavior an
Chapter 14. Blockade of Neuropathic Pain by Antisense Targeting of Tetrodotoxin-Resistant Sodium Cha
Chapter 15. Antisense Approach for Study of Cell Adhesion Molecules in Central Nervous System
Chapter 16. Sequence Design and Practical Implementation of Antisense Oligonucleotides in Neuroendoc
Chapter 17. Localization of Oligonucleotides in Brain by in Situ Hybridization
Chapter 18. Use of Antisense Oligonucleotides in Human Neuronal and Astrocytic Cultures
Chapter 19. Pharmacokinetic Properties of Oligonucleotides in Brain
Chapter 20. Antisense Oligonucleotides: Preparation and in Vivo Application to Rat Brain
Chapter 21. Application of Antisense Techniques to Characterize Neuronal Ion Channels in Vitro
Section III: Antisense in Nonneuronal Tissues
Chapter 22. Antisense Inhibition of Sodium–Calcium Exchanger
Chapter 23. Targeted Delivery of Antisense Oligonucleotides to Parenchymal Liver Cell in Vivo
Chapter 24. Antisense Methods for Discrimination of Phenotypic Properties of Closely Related Gene Pr
Chapter 25. Evaluation of Biological Role of c-Jun N-Terminal Kinase Using an Antisense Approach
Chapter 26. Role of Antisense in Kidney Cells
Chapter 27. Use of Antisense Techniques in Rat Renal Medulla
Chapter 28. Antisense Approaches to in Vitro Organ Culture
Chapter 29. In Vivo and in Vitro Antiproliferative Effects of Antisense Interleukin 10 Oligonucleoti
Chapter 30. Inhibition of c-ABL Expression in Hematopoietic Progenitor Cells Using Antisense Oligode
Chapter 31. Cellular Pharmacology of Antisense Oligodeoxynucleotides
Chapter 32. Application of Antisense Oligodeoxynucleotides for Suppression of Na /Ca2 Exchange
Chapter 33. Optimizing Efficacy of Antisense Oligodeoxynucleotides Targeting Inhibitors of Apoptosis
Section IV: Antisense in Therapy
Chapter 34. In Vitro and in Vivo Modulation of Transforming Growth Factor beta1 Gene Expression by A
Chapter 35. Analysis of Cancer Gene Functions through Gene Inhibition with Antisense Oligonucleotide
Chapter 36. Dosimetry and Optimization of in Vivo Targeting with Radiolabeled Antisense Oligodeoxynu
Chapter 37. Antisense Oligonucleotide Therapy of Hepadnavirus Infection
Chapter 38. Preclinical Antisense DNA Therapy of Cancer in Mice
Chapter 39. Retrovirally Mediated Delivery of Angiotensin II Type 1 Receptor Antisense in Vitro and
Author Index
Subject Index