(eBook) Frontiers in Cancer Research – Evolutionary Foundations by Carlo C. Maley

This is the PDF eBook version for Frontiers in Cancer Research – Evolutionary Foundations, Revolutionary Directions by Carlo C. Maley, Mel Greaves

Table of Contents

Introduction: Evolution in Cancer (Carlo Maley and Lauren Merlo)

Section I: Neoplastic Progression

Epigenetics of clonal evolution in neoplastic progression (Brian Reid)
The population genetics of neoplasms (Mary Kuhner, Simon Tavare or Josh Plotkin)
Diversity in neoplasms (Lauren Merlo)
How do clones expand? (Doug Brash)
Evolution of cancer stem cells (Darryl Shibata & Simon Tavare)
Competition and parasitism in and around neoplasms (TBD)
Cooperation in and around neoplasms (Thea Tlsty or Charis Eng)
Evolution of metastasis (James Talmadge, Rene Bernards or Bob Weinberg)
Section II: Interventions

Clonal evolution in cancer prevention (Ernie Hawk or Scott Lippman)
How to design multidrug therapy (TBD)
Drug scheduling and selection for resistance (Natalia Komarova, Franziska Michor or E.A. Gaffney)
Cechaxia and other causes of cancer mortality (John Pepper)