(eBook) Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity By Akihiko Yoshimura

This is the PDF eBook version for Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity By Akihiko Yoshimura

Table of Contents

Regulatory T cells: molecular and cellular basis for immunoregulation.- Overview of LAG-3- expressing, IL-10-producing regulatory T cells.- Regulatory Dendritic Cells.- Role of PD-1 in immunity and diseases.- CTLA-4, an essential immune-checkpoint for T cell activation.- Tim-3, Lag-3, and TIGIT.- SOCS1: regulator of T cells in autoimmunity and cancer.- Mining the complex family of protein tyrosine phosphatases for checkpoint regulators in immunity.- Immune regulation by ubiquitin tagging as checkpoint code.- MicroRNA in Immune Regulation.