(eBook) Diabetes and Viruses by Keith Taylor

This is the PDF eBook version for Diabetes and Viruses by Keith Taylor, Heikki Hyïty, Antonio Toniolo, Arie J. Zuckerman

Table of Contents

Preface.- Historical Background: Virus Involvement in diabetes.- Historical Background: Autoimmune Diabetes.- Genetics of Type 1 Diabetes.- Non-genetic Factors in the Pathogenesis of Type 1 daibetes.- EMC Virus in Mice.- AZ Enteroviruses in the Mouse Model of Type 1 Diabetes.- Kilham Virus in rats.- Reoviruses in Mice.- Ljungan Virus.- Virus-related Diabetes in Cattle.- Epidemiology of Viruses in Type 1 Diabetes.- Molecular Biology of Enteroviruses.- Laboratory Diagnosiws of Enterovirus Infection.- Enterovirus Immunity and the “Hygeine Hypothesis”.- Enteroviruses in Blood.- Coxsackieviruses and Insulitis.- Viruses in the Pancreas in Diabetes.- Other Possible Diabetogenic Viruses: Rotavirus.- Viruses, Diabetes and Autoimmunity: Studies of Subjects at Genetic Risk for Type 1 Diabetes.- Diabetes and Viruses in the Tropics.- Diabetes and Viruses in Australia and the Pacific.- Fulminant Diabetes in Japan.- Defining Causal Relationship: From Outbreak Workup to Clinical Trial.- The nPOD Research Organization.- Genes, Viruses and Molecular Mimicry.- Innate and Cell-mediated Immunity to Enteroviruses.- Innate Responses to Diabetes-Producing Viruses.- Virus Infection of Human Islets In Vitro.- Virus-Induced Cytokines in Human Islets.- Antibody Enhancement of Enterovirus Infection.- Speculation on Diabetes Prevention.- Viruses as Major Environmental Factors for the Induction of Diabetes.- Sumary and Perspectives.- Index.