(eBook) Circadian Clocks by Achim Kramer, Martha Merrow

This is the PDF eBook version for Circadian Clocks by Achim Kramer, Martha Merrow

Table of Contents

Preface.- Part I.-Molecular and cellular basis of circadian clocks.-Molecular components of the mammalian circadian clock. The epigenetic language of circadian clocks. Peripheral circadian oscillators in mammals. The clock in the brain – neurons and networks in daily rhythms. Entrainment of circadian clocks.- Part II.-Circadian control of physiology and behavior.- Circadian clocks and metabolism. Circadian control of the immune system. The circadian control of sleep. Circadian clocks in mood-related behaviors.- Part III.- Chronopharmacology and chronotherapy.- The role of clock genes in pharmacology. Circadian timing in cancer treatments. Pharmacological modulators of the circadian clock as potential therapeutic drugs. The circadian system in shift-workers.- Part IV.-Systems biology of circadian clocks.- Mathematical modeling of circadian clocks. Transcriptional circuits in the mammalian circadian oscillator. Genome-wide analyses of circadian systems