(PDF) Prospects for Chemoprevention of Colorectal Neoplasia by Andrew T. Chan

This is the PDF eBook version for Prospects for Chemoprevention of Colorectal Neoplasia – Emerging Role of Anti-Inflammatory Drugs by Andrew T. Chan, Elmar Detering

Table of Contents

What is chemoprevention today?- Mechanistic aspects in tumor development and progression of colorectal adenoma and carcinoma.- Mode of action of aspirin as a chemopreventive agent.- Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials.- COX-2 active agents in chemoprevention (includes aspirin, coxibs, and DFMO).- New potential developments in aspirin/NSAID derivatives.- Aspirin in CRC chemoprevention in the context of other chronic diseases.- Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal adenoma and carcinoma.- Genetic risks for CRC and hereditary forms of CRC. – Strategies for prevention in high risk population.