(eBook) Diabetic Cardiomyopathy – Biochemical and Molecular Mechanisms by Belma Turan

This is the PDF eBook version for Diabetic Cardiomyopathy – Biochemical and Molecular Mechanisms by Belma Turan, Naranjan S. Dhalla

Table of Contents

Cardiac defects in diabetes.- Hormonal imbalance and neuropathy.- Role of oxidative stress.- Role of cation channel defects.- Abnormalities in glucose transport.- Fatty acid utilization.- Sarcolemmal Na -K ATPase.- Sarcolemmal Ca2 -transport.- Sarcoplasmic reticular Ca2 -transport.- Intracellular Ca2 -homeostasis.- Mitochondrial function.- Contractile proteins.- ß-adrenoceptor mechanisms.- Protein kinases and signal transduction.- Regulation of phopholipases.- Endothelin defects and cardiac dysfunction.- Metabolic changes in smooth muscles.- Metabolic defects in skeletal muscles.- Metabolic defects in brain.- Role of microangiopathy in heart dysfunction.- Role of nephropathy in heart dysfunction.- Prevention of diabetic-induced cardiac dysfunction.- Molecular targets for the therapy of diabetic cardiomyopathy.